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Thursday, Jun 6

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Study shows ivonescimab improves progression-free survival in EGFR+ lung cancer

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For patients with non-small cell lung cancer with the epidermal growth factor receptor (EGFR) variant, ivonescimab plus chemotherapy improves progression-free survival, according to a study published online May 31 in the Journal of the…

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New method allows quick measurement of photoreceptor response

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Photoreceptors are the fundamental component of the entire vision process. These specialized cells that absorb light and trigger a specific physiological reaction in the body come in two varieties: cones (responsible for sharp color vision…

Study identifies molecular profile of rheumatoid arthritis patients with increased cardiovascular risk

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Rheumatoid arthritis is an autoimmune disease of unknown origin that affects around 18 million people worldwide, according to World Health Organization data. It produces chronic inflammation that mainly affects the joints. In addition, it…

Researchers report positive long-term results from study on chronic rhinitis treatment

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Neurent Medical, a company pioneering innovative non-surgical interventions to treat chronic inflammatory sinonasal diseases, today announced the publication of positive 12-month results from the CLARITY clinical trial in Laryngoscope…

Targeting bile acid pathways offers hope for liver disease treatment

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Bile acids are essential molecules the liver produces that play a critical role in digestion. They help us absorb fat-soluble vitamins and cholesterol from our food. However, bile acids can become a double-edged sword. While they are…

High levels of novel biomarker GDF15 in steatotic liver patients linked to increased liver cancer risk

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Researchers at Osaka University have found that patients with steatotic liver disease who have high levels of growth differentiation factor 15 (GDF15) in their blood are more likely to develop liver cancer. By combining blood GDF15 levels…

Diet-induced inflammation positively tied to marker of heart failure

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There is a positive correlation between diet-induced inflammation and a heart failure biomarker, according to a study published online June 5 in PLOS ONE.

Novel radiotracer rapidly detects gastrointestinal cancer biomarker, identifies patients for targeted therapy

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A new PET radiotracer enables same-day imaging of the important gastrointestinal cancer biomarker known as Claudin18.2 (CLDN18.2). Uptake of the radiotracer, 68Ga-NC-BCH, was found to correlate significantly with CLDN18.2 expression, a…

Metabolic parameters found to be similar in children born via frozen versus fresh embryo transfer, research shows

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Children born via frozen embryo transfer have similar metabolic profiles to those born via fresh embryo transfer, according to a study published June 6 in the open-access journal PLOS Medicine by Linlin Cui and Zi-Jiang Chen from Shandong…

Researchers identify key differences in inner workings of immune cells

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Cytotoxic T cells are an important component of the immune system. Once activated, they differentiate into either short-lived effector cells or long-lived memory cells. Studies by researchers at ETH Zurich have found that the cellular…

Researchers detail molecular pathway that impacts pancreatic cancer progression and treatment response

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Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have established the most comprehensive molecular portrait of the workings of KRAS, a key cancer-causing gene or "oncogene," and how its activities impact pancreatic…

New initiative aims to integrate clinical research in everyday primary care settings

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The National Institutes of Health (NIH) is investing approximately $30 million in total over fiscal years 2024 and 2025 to pilot a national primary care research network that integrates clinical research with community-based primary care.…

Epstein-Barr virus and brain cross-reactivity: Possible mechanism for multiple sclerosis detected

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The role that Epstein-Barr virus (EBV) plays in the development of multiple sclerosis (MS) may be caused by a higher level of cross-reactivity, where the body's immune system binds to the wrong target, than previously thought.

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Study finds omega-3 therapy prevents birth-related brain injury in newborn rodents

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An injectable emulsion containing two omega-3 fatty acids found in fish oil markedly reduced brain damage in newborn rodents after a disruption in the flow of oxygen to the brain near birth, a study by researchers at Columbia University…

Precision laser surgery cuts focal epileptic seizure spread

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In a busy hospital waiting room, a young man's muscles began contracting in a harsh, unyielding spasm as a quick-acting student rushed to his aid.

Long COVID's toll outlined in new report

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Long COVID continues to plague millions of Americans as the health costs of the pandemic linger four years later, a new report warns.

Gender-specific social factors may reduce the risk of cardiovascular disease

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Differences in social factors that may reduce cardiovascular disease (CVD) risk for men and women have been identified by Monash University-led research using a field of artificial intelligence (AI).

Researchers find flavor restrictions affect tobacco buyers differently depending on socioeconomic status

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Restricting menthol flavor in cigarettes while making nicotine replacement therapy, such as a skin patch that can help ease withdrawal, more available and affordable has the potential to reduce socioeconomic disparities in tobacco use.

Younger children are more commonly diagnosed with ADHD than their older classmates, says new study

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New research, led by experts at the University of Nottingham, has found that teachers may be attributing signs of age-related immaturity in children, to conditions such as Attention-Deficit/Hyperactivity Disorder (ADHD) or Autism Spectrum…

Study finds mpox continues to circulate at low numbers among gay and bisexual men who have sex with men

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While mpox cases have sharply declined since the 2022 global outbreak, they continue to occur in the U.S. among gay and bisexual men who have sex with men (GBMSM), according to a UCLA-led study from EMERGEncy ID NET, a multi-site…

Community-based screening analysis emphasizes need for hypertension screening in young athletes

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A substantial portion of are at risk of hypertension, according to a study presented at the American College of Cardiology's Care of the Athletic Heart conference, held June 6–8 in Washington.

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Unpaid care disproportionately affects low-income households across Europe

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Unpaid care has a huge impact on mental health and is more likely to be provided by people from low-income households, finds a landmark Europe-wide study by researchers at UCL and St George's, University of London. The Eurocare research…

Researchers say AI blood test provides a reliable way to identify lung cancer

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Using artificial intelligence technology to identify patterns of DNA fragments associated with lung cancer, researchers from the Johns Hopkins Kimmel Cancer Center and other institutions have developed and validated a liquid biopsy that…

New combination therapy shows promise for bladder cancer patients unresponsive to standard treatment

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In an advance that could transform bladder cancer treatment, a novel combination of cretostimogene grenadenorepvec and pembrolizumab has shown remarkable efficacy in patients with Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle…

Study suggests novel ways to use e-cigarette packaging to better protect consumers

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E-cigarette packaging could be used to encourage smokers to switch to vaping and deter non-smokers from taking up the habit, according to new research from the University of Stirling.

Why do we love to see unlikely animal friendships? A psychology expert explains

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The internet is awash with stories and videos of unlikely animal friendships, often with many millions of views. This content typically shows animals from different species showing affection to one another, signifying a bond or even a …

FDA panel OKs new COVID vaccine for fall

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A U.S. Food and Drug Administration advisory panel on Wednesday recommended updating the formula for COVID vaccines ahead of a fall campaign that will encourage Americans to get the latest shots.

What toilet paper and game shows can teach us about the spread of epidemics

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How can we explain and predict human behavior? Are mathematics and probability up to the task, or are humans too complex and irrational?

The disproportionate toll that COVID-19 took on people with diabetes continues today

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At the start of the pandemic, many people living with diabetes were wondering what COVID-19 meant for them. Diabetes was already known to put people at higher risks from other infectious diseases, including flu. Would it be the same with…

Study uncovers how cancer stem cells spread and resist treatment

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NDORMS researchers have identified a critical axis that controls the formation and behavior of cancer stem cells (CSCs), a subpopulation of cells that influence how lethal the cancer can be, its resistance to chemotherapy, and its ability…