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Study uncovers cell type-specific genetic insights underlying schizophrenia

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Schizophrenia is a complex disease with variable presentations, and the diverse nature of this mental health disorder has made understanding the mechanisms that cause the disease, and subsequently developing effective treatments,…

A promising approach to develop a birth control pill for men

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The world's population has increased by more than 2.6-fold in the last 60 years. The growing trend continues—projections indicate that the number of people living on our planet will grow to 9 billion by 2037 from 8 billion in 2022. These…

Sequencing of the developing human brain uncovers hundreds of thousands of new gene transcripts

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A team led by researchers at UCLA and the University of Pennsylvania has produced a first-of-its kind catalog of gene-isoform variation in the developing human brain. This novel dataset provides crucial insights into the molecular basis of…

Two studies offer key insights into the origins and potential treatment of mental health disorders

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Working under the umbrella of the PsychENCODE Consortium, the mental health research project established in 2015 by the National Institutes of Health, a team of Mount Sinai scientists has uncovered important new insights into the molecular…

Researchers unveil shared and unique brain molecular dysregulations in PTSD and depression

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A comprehensive approach that examines the intersection of multiple biological processes is necessary to elucidate the development of stress-related disorders. In a new study, investigators from McLean Hospital, a member of the Mass…

Tracking the cellular and genetic roots of neuropsychiatric disease

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A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer's disease.

Study explains why the brain can robustly recognize images, even without color

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Even though the human visual system has sophisticated machinery for processing color, the brain has no problem recognizing objects in black-and-white images. A new study from MIT offers a possible explanation for how the brain comes to be…

Inhibiting a metabolic pathway provides new approach to Epstein-Barr virus and resulting diseases

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The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers. Emerging data now show that inhibition of a specific metabolic pathway in infected cells can diminish latent infection and therefore the risk of…

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'What attracts audiences to pornography?' Study sheds light on online audience's state of mind

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New research conducted at Charles Darwin University (CDU) is among the first to consider the role of 'content creators' within the modern pornography landscape.

Bird flu is hitting Australian poultry farms—the first human case has been reported in Victoria

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The first human case of avian influenza (bird flu) in Australia was reported yesterday in Victoria. A child acquired the H5N1 strain of the virus in India and became ill upon returning home to Australia in March this year.

The bacteria in your mouth are important for your health—four diseases linked to your oral microbiome

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Your mouth is one of the most diverse habitats in the human body. It contains over 700 known species of bacteria, as well as yeasts, viruses and some protozoa. This community is collectively referred to as the oral microbiome—and like your…

Study further illuminates ability of cancer drug to lower blood sugar

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University of Oklahoma researchers have deepened their understanding of a drug's ability to prevent fat buildup in the liver, a condition that often occurs with obesity and can lead to serious fatty liver disease. Their findings—which…

Dehydration in middle-aged and older adults may lead to attention challenges

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Dehydration can lead to a wide array of mild to severe symptoms, from temporary inconveniences on mood to life-threatening concerns. Researchers in the Penn State Department of Biobehavioral Health studied how dehydration affects cognitive…

Heat waves can be deadly for older adults: An aging population, rising temperatures mean millions are at risk

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A deadly heat wave gripped large regions of Asia for weeks in April and May 2024. As temperatures climbed past 110°F (43.3°C) in India on May 7, campaigning politicians, local news announcers and voters waiting in long lines passed out…

Knowing why more veterans and active duty service members are dying by suicide than in battle may aid prevention

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Although service members know they may lose their lives in combat in service of their country, they may not expect to lose their lives—or those they love—to suicide. A 2021 study estimated that four times as many active duty service…

Pets give companionship, cuddles and joy—and also unavoidable stresses

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Owning a pet can be a roller coaster. There are the highs, like when your dog greets you with a full-body wiggle when you return home, or when your cat purrs loudly as you cuddle next to one another. Then there are the lows, like stressful…

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It's not just retiring athletes who need mental health support—young sportspeople need it, too

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Retiring from professional sport can be anguishing for some athletes.

Parenting a perfectionist? Here's how you can respond

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Some children show signs of perfectionism from early on. Young children might become frustrated and rip up their drawing if it's not quite right. Older children might avoid or refuse to do homework because they're afraid to make a mistake.

Researchers develop experimental mRNA avian flu vaccine

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An experimental mRNA vaccine against avian influenza virus H5N1 is highly effective in preventing severe illness and death in preclinical models. The vaccine could potentially help manage the outbreak of the H5N1 virus currently…

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Does it matter if your kids listen to you? When adolescents reject mom's advice, it still helps them cope

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Parents are often eager to give their adolescent children advice about school problems, but they may find that youth are less than receptive to their words of wisdom. However, kids who don't seem to listen to their parents may still…

Video: Does intermittent fasting increase heart disease risk?

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For years, people have used intermittent fasting to lose unwanted pounds, while others fast for religious reasons. The popular diet trend is generally safe, but some studies suggest that time-restricted eating could cause heart problems.

Researchers investigate how sense of belonging to a social group can impact food choices

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New research from Flinders University has revealed that feeling a sense of belonging to a social group can have a significant impact on our food choices, potentially nudging us towards healthier options.

How family economic insecurity can hurt child mental health

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Economic difficulty caused by the COVID-19 pandemic led to a cascade of connected problems for some parents—resulting in mental health problems for their children, a new study suggests.

Children exposed to SARS-CoV-2 in womb or as newborns may face increased social and respiratory problems

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Children who were exposed to SARS-CoV-2 (COVID-19) while in the womb or as newborn babies may face greater difficulties with social skills and have more respiratory symptoms than non-exposed children, according to a new University of…

Investigating self-harm and digital technology overuse in young people with lived mental health experience

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New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London, in partnership with YoungMinds—a UK's children's mental health charity—has found high levels of problematic mobile phone use,…

Tracking down the genetic causes of lupus to personalize treatment

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Lupus is a lifelong, often painful and occasionally lethal autoimmune disease. Few treatments exist today beyond powerful steroids to knock down a patient's immune system—a therapy that has its own serious risks.

Sleep restriction tied to negative cognitive effects in teens with overweight, obesity

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Adolescents with overweight or obesity may be more vulnerable to negative cognitive effects following sleep restriction, according to a study published online May 20 in JAMA Neurology.

Exposure to endocrine-disrupting chemicals in utero associated with higher odds of metabolic syndrome in children

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The term 'metabolic syndrome' (MetS) encompasses a group of factors, such as abdominal obesity, hypertension and insulin resistance, that together increase the risk of cardiovascular disease and type 2 diabetes.

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Tumor mutations may not predict response to immunotherapy, study finds

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The number of mutations in the DNA of cancerous tumors may not be an indicator of how well patients will respond to immune checkpoint inhibitors (ICIs), a commonly prescribed type of immunotherapy, a team led by UT Southwestern Medical…

Researchers decipher mechanisms of liver regeneration

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Scientists from the Berlin Institute of Health at Charité (BIH) and Open Targets together with colleagues from the University of Cambridge, and Addenbrooke's Hospital in Cambridge, U.K., uncovered mechanisms driving regeneration of the…