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Wednesday, Mar 27

22

Researchers turn back the clock on cancer cells to offer new treatment paradigm

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Scientists reversed an aggressive cancer, reverting malignant cells towards a more normal state. Rhabdoid tumors are an aggressive cancer which is missing a key tumor suppressor protein. Scientists discovered that removing a second protein…

Getting too little sleep linked to high blood pressure

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Sleeping fewer than seven hours is associated with a higher risk of developing high blood pressure over time, according to a new study.

Social, environmental factors may raise risk of developing heart disease and stroke

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Neighborhoods with more adversity have up to twice the increased risk of heart disease and stroke, according to a new study.

21

New technique for predicting protein dynamics may prove big breakthrough for drug discovery

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Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers has developed a way of using machine learning to rapidly predict multiple…

Risk factors for faster aging in the brain revealed in new study

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Researchers have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia.

Popular obesity drugs may lead to medical procedure complications

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New research suggests people who are scheduled for certain medical procedures should stop taking popular weight loss drugs in the days or weeks prior to avoid complications.

20

Safer, more efficient drug discovery

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Researchers have discovered a safer and more efficient technique for testing new drugs while they are in development.

Old immune systems revitalized in mouse study, improving vaccine response

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Those with aging immune systems struggle to fight off novel viruses and respond weakly to vaccination. Researchers were able to revitalize the immune system in mice.

19

Sweet success: Sugarcane's complex genetic code cracked

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Scientists created a highly accurate reference genome for one of the most important modern crops and found a rare example of how genes confer disease resistance in plants. Exploring sugarcane's genetic code could help researchers develop…

Researchers discover a mechanism that could improve platinum-based cancer therapy

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Researchers say they have discovered that the protein puromycin-sensitive aminopeptidase (NPEPPS) plays a role in regulating response to platinum chemotherapy in patients with bladder cancer.

Couples with similar drinking habits may live longer

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The couple that drinks together might live longer together, too, says a University of Michigan researcher.

Memory self-test via smartphone can identify early signs of Alzheimer's disease

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Dedicated memory tests on smartphones enable the detection of 'mild cognitive impairment', a condition that may indicate Alzheimer's disease, with high accuracy.

18

Want to feel young? Protect your sleep

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Do you ever find yourself longing for the energy and vitality of your younger years? Feeling young is not just a matter of perception it is actually related to objective health outcomes. Previous studies have shown that feeling younger…

07

Silicon spikes take out 96% of virus particles

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An international research team has designed and manufactured a virus-killing surface that could help control disease spread in hospitals, labs and other high-risk environments.

04

New testing approach improves detection of rare but emerging Powassan virus spread by deer ticks

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Researchers have come up with a new, more accurate method for detecting in ticks the emerging Powassan virus, which can cause life-threatening neuroinvasive disease, including encephalitis and meningitis.

Study finds high prevalence of hidden brain changes in people with heart disease

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A new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of stroke and dementia are common in people with a range of heart conditions, regardless of whether they have…

New genetic analysis tool tracks risks tied to CRISPR edits

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While CRISPR has shown immense promise as a next-generation therapeutic tool, the gene editing technology's edits are still imperfect. Researchers have developed a new system to test and analyze CRISPR-based DNA repair and related risks…

03

Researchers show that introduced tardigrade proteins can slow metabolism in human cells

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Tardigrade proteins are potential candidates in technologies centered on slowing the aging process and in long-term storage of human cells.

Optimizing electronic health records: Study reveals improvements in departmental productivity

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Researchers identify transformative effects of electronic health record (EHR) optimization on departmental productivity.

Just ask: Patients in the ER are willing to get a flu shot

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Simply asking patients to get the flu vaccine, and combining it with helpful video and print messages, is enough to persuade many who visit emergency departments to roll up their sleeves, according to a new study.

Tuesday, Mar 26

21

Researchers a step closer to a cure for HIV

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A new study shows virus-like particle can effectively 'shock and kill' latent HIV reservoir in those living with chronic HIV.

Genetically engineered dendritic cells enhance the power of immunotherapy against lung cancer

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A new study suggest that using CXCL9 and CXCL10-producing dendritic cells alongside immunotherapy can be a promising strategy to overcome treatment resistance and improve clinical outcomes for patients with non-small cell lung cancer.

17

Large-scale animal study links brain pH changes to wide-ranging cognitive issues

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The International Brain pH Project Consortium unveils groundbreaking findings in a large-scale animal model study, indicating altered brain pH and lactate levels as a transdiagnostic endophenotype in neuropsychiatric disorders with…

16

New treatment target identified for Alzheimer's disease

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Researchers have identified a new potential target for the treatment of Alzheimer's disease -- PDE4B. The researchers observed that AD mice showed memory deficits in maze tests, but memory was unimpaired in AD mice with genetically reduced…

Common degenerative brain disease may begin to develop in middle age

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Lewy body disease may be more common in middle-aged people than previously thought, according to a recent study. In the study, almost one in ten of over 50-year-olds were found to have tissue markers of Lewy body disease in the brain.

xCT protein is key link in inhibiting pancreatic cancer growth and limiting mood disturbances

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The xCT protein, which plays an important role as a transport molecule in the cell, could play a part in cancer treatment in the future, researchers have discovered. Their recent studies on mice show that targeting the protein can not only…

Young adults with migraine, other nontraditional risk factors may have higher stroke risk

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Nontraditional risk factors such as migraines are as important as traditional risk factors like high blood pressure for adults younger than ages 35-45, finds new study.

04

Gene discovery offers new hope for people living with chronic skin disease

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Scientists have discovered a gene mutation is responsible for causing psoriasis -- a chronic inflammatory skin disease that causes patients to develop red, scaly and itchy patches across their body. According to researchers, if two copies…

Monday, Mar 25

00

Human brains are getting larger: That may be good news for dementia risk

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A new study has found human brains are getting bigger. The increased size may lead to a brain reserve, potentially reducing the risk of dementia.

23

More exposure to artificial, bright, outdoor night-time light linked to higher stroke risk

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Air pollution and night-time outdoor light each were associated with harmful effects on brain health, finds new study.