The rapidly spreading monkeypox outbreak represents a global health emergency, the WHO's highest level of alert, Director-General Tedros Adhanom Ghebreyesus said on Saturday. Reuters Health Information
Being physically fit protected against the increased risk of developing chronic kidney disease that is associated with low socioeconomic status in a study of middle-aged men in Finland. Medscape Medical News
Low plasma levels of ATPase inhibitory factor 1, a novel risk factor, in people with prediabetes has been significantly linked with subsequent development of type 2 diabetes in a prospective study. First Look
A US neuroscientist claims that some of the studies of the experimental agent, Simufilam, a drug that targets amyloid beta in Alzheimer's disease, are flawed and has taken his concerns to the NIH. Medscape Medical News
Hormone therapy did not increase mortality in postmenopausal women treated for early-stage estrogen receptor–positive breast cancer, but there was a recurrence risk with vaginal estrogen therapy. MDedge News
Experts have expressed concern that men with low-risk disease who are currently followed with active surveillance may be targeted with expensive therapies that have potentially serious side effects. Medscape Medical News
The novel gene therapy normalized and stabilized factor IX levels in 9 of 10 patients with moderate to severe hemophilia B, removing the need for regular injections. Medscape Medical News
Researchers have been trying to determine who faces a higher risk for developing long COVID, with symptoms that can last for weeks, months, or years after the initial infection. WebMD Health News
A meta-analysis of 82 randomized clinical trials in people with type 2 diabetes run worldwide showed marked under-representation of people from non-White racial and ethnic groups despite a high disease prevalence. First Look
Copper modifies and accelerates alpha synuclein aggregation, offering potential inroads to novel methods of detecting and treating Parkinson's disease, new research suggests. MDedge News
Simultaneous administration of a COVID-19 mRNA booster shot and the flu vaccine slightly increases the risk of systemic reactions, but most of them are mild. Medscape Medical News
Some people living with HIV and some state health officials are raising concerns about part of the federal effort to end the HIV epidemic: a new technology that analyzes blood samples to find outbreaks. Kaiser Health News
A Medscape poll reveals that doctors want patients to understand how many challenges they have, as well as how much work they do to take care of patients. Medscape Medical News
The Apollo Endosurgery devices are the first and only ones approved by the FDA for endoscopic sleeve gastroplasty (ESG) and endoscopic bariatric revision, the company says. FDA Approvals
A new study published in the Lancet shows young adults aged 15–34 derive no significant health benefits from alcohol consumption, but moderate drinking may benefit those over 40. Medscape Medical News
Risks for hospitalizations, IBD-related surgeries, and serious infections were significantly higher among Hispanic patients in the year after starting a biologic compared with non-Hispanic patients. Medscape Medical News
Results from a randomized study of 36 adults with subacute thyroiditis showed that starting patients on a daily prednisolone dose of 15 mg/day was noninferior to starting them on a daily 30-mg dose. First Look
A new study lays the groundwork for considering time burden as an adverse event in cancer trials. This study summary was published on medrxiv.org as a preprint and has not yet been peer reviewed. First Look
An analysis of lung cancer screening since March 2021, when eligibility criteria were expanded, shows that significantly more Black men have been screened, but not women or undereducated people. Medscape Medical News
Children exposed to maternal PCOS were hospitalized at higher rates for conditions like asthma and pneumonia, according to a Canadian study. Medscape Medical News
The US Food and Drug Administration has approved zonisamide oral suspension (Zonisade) as adjunctive therapy for partial seizures in adults and teens 16 years and older with epilepsy. Medscape Medical News
Playing video games can alter the brain to improve higher-order cognitive skills, including decision-making, according to new findings that have potential implications for brain training. Medscape Medical News
A review of cases of lymph node–positive prostate cancer found that patients fare better if they receive up-front adjuvant radiotherapy (RT) after prostatectomy rather than wait for salvage RT. Medscape Medical News
In-hospital death in patients with acute COVID-19 was more likely in those with RV dysfunction or dilation, and more likely than in patients with other respiratory diseases, in an observational study. First Look
Though the study identified better overall survival among married patients, the findings more likely represent a proxy for a stronger support network rather than an effect from marital status itself. Medscape Medical News