Shohei Ohtani went 4-for-5 with two RBIs, finishing a home run shy of the cycle, in the Los Angeles Angels' 9-6 loss to the Houston Astros on Saturday.
In his second start as the leadoff batter this season, the two-way star singled twice, doubled and tripled at Minute Maid Park, a day after he pitched.
Ohtani singled to right field in his final at-bat of the game in the ninth inning, giving him four hits in a game for the second time this season.
The Angels have dropped the first three of their four-game series in Houston.
Alex Bregman hit a grand slam in the fourth inning to extend the Astros' lead to 7-1 before the Angels got back in the game with a four-run seventh.
Ohtani has hit for the cycle once in his major league career, on June 13, 2019, against the Tampa Bay Rays in St. Petersburg, Florida.
At Petco Park, Yu Darvish pitched seven dominant innings to lead the San Diego Padres to a 6-0 win over the Chicago Cubs.
Darvish (4-4) held the lineup, including Japanese compatriot Seiya Suzuki, to two hits, both singles, while striking out nine and walking one in a 115-pitch outing.
Suzuki went hitless in four at-bats, striking out three times.
Boston Red Sox rookie Masataka Yoshida had a total of three hits with an RBI in a doubleheader against the AL East-leading Rays. The Red Sox took the first game 8-5 and the Rays won the next 4-2.