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12

SARS-CoV-2 evolves after jumping from humans to zoo animals

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Research on SARS-CoV-2 in zoo tigers, lions, and hyenas shows rapid viral evolution and adaptation, offering insights into cross-species transmission dynamics.

11

What Americans eat is driving global nutrition research

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WWEIA data, a cornerstone of national dietary surveillance, drives nutrition research and policy, enhancing understanding of dietary trends and health outcomes.

10

New in vitro platform predicts drug toxicity, improving cancer treatment safety

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Overcoming acquired treatment resistance is one of the major challenges in the fight against cancer. While combination therapies hold promise, their toxicity to healthy tissue remains a major hurdle. To anticipate these risks, researchers…

Study reveals significant financial strain on families seeking mental healthcare

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Behavioral health care has surged to represent 40 % of all medical expenditures for U.S. children in 2022, nearly doubling from 22 % in 2011, according to a new study published in JAMA Pediatrics. Researchers found that pediatric…

Scientists discover rapid synapse adaptation in neuronal communication

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Every movement you make and every memory you form depends on precise communication between neurons. When that communication is disrupted, the brain must rapidly rebalance its internal signaling to keep circuits functioning properly.

09

Mediterranean diet and healthy habits improve cancer survival rates

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Being more physically active, following a balanced diet, not smoking, and keeping body weight and blood pressure under control: the same habits that protect the heart also prove decisive after a cancer diagnosis.

New research highlights the importance of social engagement for cognitive health

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New research from the University of St Andrews has discovered a direct causal effect between social isolation and a faster decline in later- life cognitive function. Pathological cognitive decline is most often driven by Alzheimer's and…

06

Blood-based biomarkers and the new landscape of Alzheimer’s research

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For much of the past century, Alzheimer's disease has been one of medicine's most daunting frontiers—biologically complex, devastating in impact, and difficult to diagnose early.

Scientists map how cinnamon’s bioactives interact with cancer signaling

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This review synthesizes preclinical evidence showing that cinnamon-derived compounds can modulate inflammation, oxidative stress, apoptosis, and angiogenesis through multiple cancer-related signaling pathways. While biologically plausible,…

05

Indoor tanning loads normal skin with mutations linked to melanoma

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Indoor tanning is associated with markedly higher mutation burdens and cancer-driving genetic changes in melanocytes taken from normal-appearing skin, including areas usually protected from sunlight. These molecular alterations provide a…

Circadian control of neutrophils limits heart damage after myocardial infarction

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Neutrophils cause time-of-day–dependent collateral tissue damage after sterile injury through an intrinsic circadian program. Activating a CXCL12–CXCR4 checkpoint repositions neutrophils, limiting inflammatory injury without impairing…

04

Gut bacteria patterns differ in autism and siblings and link to social symptoms

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This sibling-controlled East Asian study found that autistic individuals, their unaffected siblings, and typically developing controls differ in gut microbiota diversity and composition, with the clearest separation between autism and…

New initiative aims to transform care for early-onset cancer patients

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More people under age 50 are developing cancer, and with that comes a shift in the model of care needed to serve this unique cancer patient population – including early access to fertility counseling, universal genomic testing to identify…

GDF3 protein sustains harmful inflammation in aging immune cells

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As people age, their bodies develop a dysfunctional immune system, which can leave older adults more susceptible to conditions like sepsis.

AI uncovers hidden mechanisms of covert attention and emergent neuron types

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Shifting focus on a visual scene without moving our eyes - think driving, or reading a room for the reaction to your joke - is a behavior known as covert attention.

Chemotherapy may reduce HIV-infected T cells

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Advancements in HIV/AIDS research, drug development and clinical practice since the 1980s have made it possible for people living with HIV to lead long, productive lives and keep the virus in check at undetectable levels and…

Researchers explore how the visual brain system recovers following traumatic injury

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The brain shows a capacity to recover from traumatic injury, which somewhat contradicts the widely accepted idea that neurons do not regenerate.

Smartwatch alerts help parents manage children's tantrums

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Mayo Clinic researchers have developed a smartwatch-based alert system that signals parents at the earliest signs of a tantrum in children with emotional and behavioral disorders - prompting them to intervene before it intensifies.

Breast cancer disrupts stress hormone rhythms in the brain

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"The brain is an exquisite sensor of what's going on in your body," says Cold Spring Harbor Laboratory Assistant Professor Jeremy Borniger. "But it requires balance. Neurons need to be active or inactive at the right times. If that rhythm…

Researchers uncover how Bartonella causes deadly Oroya fever

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The so-called "Oroya fever" is an extremely severe infectious disease, yet it is classified among the so-called neglected tropical diseases.

ADHD linked to higher risk of criminal convictions and family patterns

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A largescale, comprehensive study has found that individuals with attention-deficit/hyperactivity disorder (ADHD) are at increased risk of being convicted of crimes compared to those without ADHD, and that this association extends to their…

Air pollution and immune changes could trigger autoimmune conditions

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A new study has linked air pollution exposure and immune-system changes that often precede the onset of autoimmune diseases.

Advances in delivering oxygen-sensitive gut bacteria improve microbial therapies

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Recent research has identified practical ways to protect and deliver oxygen-sensitive gut bacteria for a path toward safer, standardized microbial therapies that could reduce reliance on donor-based faecal microbiota transplants.

Researchers block virus entry by targeting key protein interaction

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Washington State University researchers have found a way to modulate a common virus protein to prevent viruses from entering cells where it can cause illness, a discovery that could someday lead to new antiviral treatments.

Canada's reduced Global Fund pledge threatens health at home and abroad

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Canada should rethink its reduced pledge to the Global Fund to protect the health of people in Canada as well as around the globe, argue authors in an editorial published in CMAJ.

New framework tracks response to anti-amyloid therapies in Alzheimer's

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In the last few years, progress has been made in the fight against Alzheimer's disease with a class of therapies called anti-amyloid antibodies (anti-Aβ).

03

COVID 19 vaccination protects pregnant people and their babies

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Pregnant people who received a COVID-19 vaccine were far less likely to experience severe illness or deliver their babies prematurely, according to a major new UBC-led study published in JAMA.

Blood test identifies colon cancer patients who benefit from anti-inflammatory medication

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A blood test could help doctors decide which patients with colon cancer should receive anti-inflammatory medication along with chemotherapy after surgery, according to new study in JAMA Oncology.

Tiny blood particles help shuttle a hormone through the body

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Researchers at Touro University Nevada have discovered that tiny particles in the blood, called extracellular vesicles (EVs), are a major player in how a group of hormones are shuttled through the body. Physical exercise can stimulate this…

Lipoic acid shows limited benefit in progressive multiple sclerosis

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The over-the-counter supplement lipoic acid may have a small beneficial effect in slowing the loss of gray matter in the brains of people with progressive forms of multiple sclerosis, according to new research led by Oregon Health &…