MIT researchers developed a compact band-pass Raman spectroscopy device that noninvasively tracks glucose through the skin in under a minute using physically interpretable optical signals. In a pilot study and tissue phantom validation,…
Long-term antidepressant use in Australia increased steadily between 2014 and 2023, with the largest relative rise seen among adolescents and young adults aged 10 to 24 years. Treatment duration also lengthened over time, while apparent…
A chemotherapy-free combination treatment outperformed a combination of targeted therapy and chemotherapy among patients with Ph+ acute lymphoblastic leukemia (ALL) in a new study.
Study shows that increasing dietary vitamin C intake with kiwifruit raises vitamin C levels in both the dermis and epidermis through active transport from the bloodstream. Higher skin vitamin C levels were associated with increased skin…
A large quasi-experimental study in Wales shows that eligibility for shingles vaccination is linked to fewer new mild cognitive impairment diagnoses and lower dementia-related mortality. Benefits appear strongest in women and are observed…
Pirtobrutinib, a non-covalent Bruton tyrosine kinase (BTK) inhibitor, met the primary endpoint for non-inferiority in terms of overall response rate in the first head-to-head comparison with ibrutinib, a covalent BTK inhibitor.
In a new trial, patients newly diagnosed with acute myeloid leukemia (AML) fared significantly better with a combined regimen of azacitidine and venetoclax compared with conventional induction chemotherapy.
In a new trial, patients with follicular lymphoma had a significantly higher response to treatment and a nearly 80% reduction in the risk of death or disease progression if they received epcoritamab in addition to the standard second-line…
Parental permissiveness toward heavy episodic drinking is higher among Greek-affiliated students and their parents during the transition from high school to college. Students who perceive greater parental approval of heavy drinking report…
Despite long-standing recommendations, a major updated Cochrane review finds that calcium supplementation during pregnancy does not meaningfully reduce pre-eclampsia risk, prompting a rethink of how best to prevent hypertensive disorders…
Human researchers outperformed large language models across all major stages of systematic review preparation, particularly in study selection, synthesis, and final manuscript drafting. While LLMs demonstrated speed and partial accuracy in…
This study shows that preoperative gait speed is a strong predictor of patient-reported pain relief, function, and joint awareness after total hip arthroplasty for osteoarthritis. A walking speed of at least 1.0 m/s before surgery…
Early exposure to fat-related food odors during development alters central sensory processing and metabolic regulation, independently of maternal obesity or nutrient intake. These sensory cues program long-term susceptibility to obesity,…
According to a new trial, patients with chronic lymphocytic leukemia (CLL) show comparable outcomes whether they receive a single-agent treatment indefinitely or a combination treatment for a fixed period of time.
In a new trial, patients with B-acute lymphoblastic leukemia (B-ALL) who had no evidence of remaining cancer cells after prior treatment, experienced comparable outcomes whether they received chemotherapy-based conditioning or total body…
Nearly a third of families with children receiving chemotherapy for acute lymphoblastic leukemia (ALL) – the most common pediatric cancer – develop serious financial difficulties during their child's treatment, including losing 25% or more…
Within a year of initiation, a multidisciplinary project to improve screening and treatment for iron deficiency in pregnancy resulted in a sixfold rise in screening rates for iron deficiency in pregnant patients, a 20-fold rise in the…
Treatment with intravenous (IV) iron significantly improved survival and increased hemoglobin levels in patients with iron-deficiency anemia who were hospitalized for an acute bacterial infection, according to an analysis of data from more…
Compared with white patients, Black patients with acute myeloid leukemia (AML) were on average more than five years younger at diagnosis, more than 30% more likely to die of their disease, and more than 20% more likely to die of any cause,…
Taking the sickle cell drug hydroxyurea during or shortly before pregnancy does not appear to cause specific issues in newborns, according to the first prospective study of pregnancies involving hydroxyurea exposure.
The first study assessing the real-world commercial roll-out of gene therapies for sickle cell disease and beta thalassemia offers lessons learned to inform best practices as manufacturers and medical centers prepare to meet growing demand…
Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms and low rates of severe side effects or complications years after their procedure, according to a new…
A new study finds that only one in three patients visiting emergency departments (EDs) for severe pain associated with sickle cell disease received appropriate opioid-based pain-relieving medications within the first hour as recommended by…
Preliminary results from two trials of the gene therapy exagamglogene autotemcel (exa-cel) suggest the therapy offers an effective cure for beta-thalassemia and sickle cell disease in children younger than 12.
Since 2000, most countries – across all income levels and regions – have made concurrent progress in expanding health service coverage and reducing the financial hardship associated with health costs, according to a new joint report from…
Psycholinguists from the Center for Language and Brain found that phonological processing skills continue to influence text reading fluency in 15-to-18-year-old adolescents.
Hospitals struggling to attract and retain enough registered nurses at the bedside are implementing alternative strategies to ensure patients get needed nursing care.