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14

GLP-1 meds prompt rethink of obesity and eating disorder care

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Obesity and eating disorders have traditionally been treated as separate areas of healthcare – but the rapid rise of GLP-1 medicines is increasingly bringing the two together.

Funding boost to strengthen Australia's drug discovery pipeline

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A WEHI-led project has received $7 million in Australian Government funding to expand the nation’s drug discovery capabilities and accelerate the translation of breakthrough research into new therapies.

09

New APIs extend Wiley's gold-standard spectral data and analytical intelligence directly into lab, vendor, and platform workflows

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Wiley, a global leader in authoritative content and research intelligence, today announced the launch of its spectral analysis application programming interface (API) portfolio, providing users with a new, faster way to access its trusted…

08

Nicoya is a famous blue zone. DNA aging estimates tell a more complicated story

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Researchers developed a SuperLearner framework that combines established epigenetic clocks with machine learning to compare DNA methylation-based aging in residents of Costa Rica’s Nicoya Blue Zone with other Costa Ricans. Initial…

07

GLP-1 drugs may reshape obesity care, but clinicians still have questions

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Interviews with 11 healthcare professionals in a UK specialist weight management service found generally positive attitudes toward injectable GLP-1 drugs, alongside limited formal training and uncertainty about how the medications should…

Sewage monitoring may provide earlier warning of pertussis outbreaks

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Pertussis, or whooping cough, continues to cause periodic outbreaks worldwide and can be especially dangerous for infants who have not completed vaccination.

Vagus nerve stimulation may enhance long-term motor learning

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Do you ever feel like sometimes you can master a new dance step almost immediately, while other times you struggle to nail it despite repeated practice? This might be due to skill or effort, but also to something less obvious: whether the…

06

Nicotine e-cigarettes help more smokers quit than conventional methods

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Nicotine e-cigarettes are more effective in helping people quit smoking than many conventional methods such as nicotine gums and patches and quitting with behavioural support or no support at all, an updated Cochrane review finds.

Why living to 100 may depend on far more than diet and exercise

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A critical narrative review found that healthy diets, regular physical activity, strong social ties, and psychological well-being can support healthier aging and reduce premature mortality, but none has been shown to reliably determine who…

Sugar tax could prevent millions of cases of tooth decay in Australia

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Millions of cases of tooth decay could be prevented if Australia introduced a 20 per cent tax on sugar, new Griffith University research has found.

Protecting the thymus may improve lung cancer treatment outcomes

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Building on recent discoveries about the adult thymus, Mass General Brigham investigators used artificial intelligence to show that incidental radiation exposure to the thymus may influence outcomes in patients with lung cancer.

New artificial lung mimics breathing and alveolar movement

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Almost everyone has blown a soap bubble through a straw at least once. Inspired by this thin soap bubble film, an "artificial lung that breathes" like a real lung has been developed.

FDA endorses alpha-synuclein biomarker for Parkinson’s clinical trials

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Critical Path Institute® (C-Path) today announced the publication of "Regulatory endorsement for the application of alpha-synuclein seed amplification assay (αSyn-SAA) as a susceptibility and risk biomarker for clinical trials targeting…

Scientists found a distinct gut microbiome pattern in people with symptomatic diverticular disease

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A multicenter Japanese study found that symptomatic uncomplicated diverticular disease (SUDD) was associated with reduced gut microbial diversity, increased abundance of the Ruminococcus gnavus group, and depletion of Coprococcus and other…

05

Study links thymus radiation to worse lung cancer outcomes

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Until recently, the thymus was thought to be of little use beyond puberty, but new research has shown that radiation to the organ is associated with worse outcomes in patients being treated for non-small cell lung cancer (NSCLC).

A year after women lost weight, researchers saw which health gains lasted and which faded

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Diet-induced weight loss significantly reduced predicted 10-year risks of major adverse cardiovascular events and type 2 diabetes in healthy premenopausal women with overweight, regardless of whether aerobic or resistance exercise was…

Internalized racial oppression may undermine culturally affirming parenting

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Black parents who experienced higher levels of appropriated racial oppression - defined as shaping one's behavior and self-concept around dominant cultural norms of whiteness - were less likely to transmit positive, culturally protective…

New UCSF center aims to improve eating disorder care

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People with eating disorders wait an average of more than two-and-a-half years between the onset of symptoms and the start of treatment.

Tissue-mimicking scaffold may enable more durable rotator cuff repairs

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Researchers have developed a "scaffold" that mimics natural tissue and could lead to more durable rotator cuff repairs, including for large injuries and cases involving bone and tissue degeneration that are often the most difficult to fix.

Study reveals how the brain balances competing goals

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How do we decide what to do when faced with choices? And how does the brain adapt those decisions as the world around us changes? A new study published in Nature by researchers at Baylor College of Medicine and Duncan Neurological Research…

Researchers traced lifelong obesity resistance in mice back to an early microbial encounter

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Natural wild-derived microbiota protected mice against diet-induced obesity across sexes, genetic backgrounds, and age by increasing energy expenditure and promoting a thermogenic program in brown adipose tissue. The effect depended on the…

Ancient proteins revived to inspire new antimicrobial treatments

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University of Oregon biologists have resurrected prehistoric proteins up to 160 million years old that carry natural antimicrobial properties.

Global snakebite burden may be far higher than previously estimated

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Venomous snake bites can cause illness, disability and death in tropical and subtropical regions. A study published on August 25th in PLOS Medicine by Dileepa Ediriweera and Anuradhani Kasturuiratne at the Liverpool School of Tropical…

Tuesday, Aug 25

23

Emergency diagnoses of medical conditions predict worse patient survival

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Patients diagnosed with conditions after an emergency hospital admission or an emergency room visit face a higher risk of death than those diagnosed in non-emergency settings, according to a large population-based study by Emma Whitfield…

Diabetes study reveals differing health risks for men and women

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In the years following type 2 diabetes diagnosis, women are more likely to develop mental health conditions, while men are more likely to develop cardiovascular and renal complications, according to a study published August 25th in the…

20

Anti-immigrant policies linked to rising HIV cases among Hispanic populations

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Following the Trump administration's 2018 announcement of changes to the public charge rule that would penalize immigrants for using public benefit programs, antisanctuary counties in the US saw a 16.8-percent increase in HIV cases among…

Scientists discover how neutrophils travel to infection sites without damaging healthy tissue

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UMass Chan Medical School scientist Beth McCormick, PhD, and her team collaborated with researchers at the University of Bath to discover how neutrophils, the body's most abundant type of white blood cells, travel to infection sites…

NIH grants support research on whether PFAS exposure increases risk of liver and endometrial cancers

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Researchers at the Keck School of Medicine of USC and USC Norris Comprehensive Cancer Center have received two grants from the National Institutes of Health (NIH) totaling $7.5 million to study whether exposure to per- and polyfluoroalkyl…

SBRT improves bowel health related quality-of-life in patients with localized intermediate-risk prostate cancer

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Results of the NRG Oncology NRG-GU005 clinical study comparing stereotactic body radiation therapy (SBRT) to moderately hypofractionated intensity-modulated radiation therapy (MH-IMRT) for patients with localized intermediate risk prostate…

Gene removal makes engineered immune cells more effective against osteosarcoma

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Scientists at St. Jude Children's Research Hospital have discovered that removing the gene for Regnase-1 from engineered immune cells makes them more effective at treating relapsed osteosarcoma.