The microscopic organisms that fill our bodies, soils, oceans and atmosphere play essential roles in human health and the planet's ecosystems. Yet even with modern DNA sequencing, figuring out what these microbes are and how they are…
Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into bone-building cells or osteoblasts, and…
Indoor dust, air and everyday products are exposing people to a growing mix of "new contaminants" inside homes, schools and workplaces, according to a new perspective published in the journal New Contaminants.
The production of cultured meat depends on the isolation, expansion, and differentiation of animal stem cells into edible tissues. Muscle stem cells, or satellite cells, are central to this process due to their ability to regenerate and…
Before you can address a problem, you need to understand its scope. That's why the United Nations developed the Integrated Food Security Phase Classification System. Aid organizations rely on analyses from this global partnership, which…
This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of neuropeptide FF receptor 1 (NPFFR1)-a Gi/o-coupled receptor that responds to endogenous RF-amide peptides (RFRP-3 from…
Fibrosis, resulting from excess extracellular matrix (ECM) deposition, is a feature of adipose tissue (AT) dysfunction and obesity-related insulin resistance.
Engineered oncolytic bacteria have emerged as a promising therapeutic platform for precision cancer treatment, offering tumor-specific colonization, immune activation, and controllable therapeutic delivery. This review summarizes recent…
DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within nucleosomes, yet their structural and functional…
The American College of Lifestyle Medicine (ACLM) applauds two new Centers for Medicare and Medicaid Services (CMS) models that could significantly reshape the landscape for lifestyle medicine practice and reimbursement.
A new study from the University of Oklahoma suggests that small genetic differences in two proteins – previously known for their role in premature infants' lungs – may also influence how their eyes develop, potentially affecting the risk…
Children with a rare form of cancer called neuroblastoma which hasn't responded to initial treatment or that has relapsed may benefit from adding antibody treatment to usual chemotherapy, according to new results from a clinical trial.
Leslie M. Thompson, Donald Bren Professor of psychiatry and human behavior as well as neurobiology and behavior at the University of California, Irvine, has received an $11,999,933 grant from the California Institute for Regenerative…
Doctors treating seriously ill patients in an emergency setting may want to give the sedative etomidate, rather than ketamine, while placing a breathing tube, according to a randomized trial published Dec. 9 in the New England Journal of…
Viruses are typically described as tiny, perfectly geometric shells that pack genetic material with mathematical precision, but new research led by scientists at Penn State reveals a deliberate imbalance in their shape that helps them…
SereNeuro Therapeutics, a preclinical biotechnology company developing non-opioid pain therapies, unveiled new data today on a novel approach to chronic pain management and joint tissue preservation.
Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in 8,000 people. While it is well known for causing muscle weakness and stiffness, DM1 also affects other organs, including the…
Tanning bed users are known to have a higher risk of skin cancer, but for the first time researchers have found that young indoor tanners undergo genetic changes that can lead to more mutations in their skin cells than people twice their…
Helen Bernie, DO, MPH, assistant professor of urology at Indiana University School of Medicine, will participate in an expert panel on testosterone replacement therapy and men's health to be held Wednesday, Dec. 10, by the U.S. Food and…
While patients with acute myeloid leukemia (AML) are routinely treated with chemotherapy and other cell-killing therapies, existing options do not lead to favorable clinical outcomes in all patients.
More than 30 people have applied for a lab technician job at West River Health Services in Hettinger, North Dakota, a thousand-person town in the rural southwestern part of the state.
Though an estimated 60 million people around the world have atrial fibrillation, or A-fib, a type of irregular and often fast heartbeat, it's been at least 30 years since any new treatments have been developed.
Premature babies are particularly susceptible to strong sensory impressions and high sound levels from the incubator. Now researchers will look at what can be done to protect children's hearing and development.
When the unthinkable happens and a child is left critically ill or injured, the miracle workers in pediatric intensive care units around the country work tirelessly to save their lives.
Researchers led by investigators at Mass General Brigham have published valuable information about a rare but serious complication of anti-cancer immunotherapy, providing the first large-scale description of its risk factors and clinical…
Mature nodal T-cell lymphoma is a type of rare and aggressive blood cancer. Limited data make it difficult to identify high-risk patients or tailor treatment strategies, so most patients receive similar care despite differences in disease…
Adolescent and young adult nicotine vaping has become an urgent public health concern, as 2024 marked the first year that nicotine vaping was the most initiated drug.
A recent review published in Current Molecular Pharmacology explores the therapeutic potential of melatonin in systemic lupus erythematosus (SLE), a complex autoimmune disease affecting multiple organs.