A chemotherapy-free combination treatment outperformed a combination of targeted therapy and chemotherapy among patients with Ph+ acute lymphoblastic leukemia (ALL) in a new study.
Study shows that increasing dietary vitamin C intake with kiwifruit raises vitamin C levels in both the dermis and epidermis through active transport from the bloodstream. Higher skin vitamin C levels were associated with increased skin…
A large quasi-experimental study in Wales shows that eligibility for shingles vaccination is linked to fewer new mild cognitive impairment diagnoses and lower dementia-related mortality. Benefits appear strongest in women and are observed…
In a new trial, patients with follicular lymphoma had a significantly higher response to treatment and a nearly 80% reduction in the risk of death or disease progression if they received epcoritamab in addition to the standard second-line…
Despite long-standing recommendations, a major updated Cochrane review finds that calcium supplementation during pregnancy does not meaningfully reduce pre-eclampsia risk, prompting a rethink of how best to prevent hypertensive disorders…
According to a new trial, patients with chronic lymphocytic leukemia (CLL) show comparable outcomes whether they receive a single-agent treatment indefinitely or a combination treatment for a fixed period of time.
Taking the sickle cell drug hydroxyurea during or shortly before pregnancy does not appear to cause specific issues in newborns, according to the first prospective study of pregnancies involving hydroxyurea exposure.
The first study assessing the real-world commercial roll-out of gene therapies for sickle cell disease and beta thalassemia offers lessons learned to inform best practices as manufacturers and medical centers prepare to meet growing demand…
Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms and low rates of severe side effects or complications years after their procedure, according to a new…
A new study finds that only one in three patients visiting emergency departments (EDs) for severe pain associated with sickle cell disease received appropriate opioid-based pain-relieving medications within the first hour as recommended by…
Preliminary results from two trials of the gene therapy exagamglogene autotemcel (exa-cel) suggest the therapy offers an effective cure for beta-thalassemia and sickle cell disease in children younger than 12.
A genetic variant is likely putting some children suffering with myocarditis - inflammation of the heart muscle - at higher risk of developing heart failure, which can be fatal, according to a study published today in Circulation Heart…
In November, The Lancet, one of the world's most esteemed medical journals, launched a new monthly series of case studies that goes beyond clinical diagnoses to illuminate the social and cultural forces that contribute to each patient's…
Recent weeks have brought good news about vaccines, with studies indicating that flu vaccination reduces heart disease, shingles vaccines can prevent or slow dementia, and a single human papilloma virus shot protects a girl from cervical…
Can doctors in California learn from a patient who was bounced from one specialist to another in Japan? Can clinicians in London take lessons from a patient seeking asylum while suffering a medical emergency at the U.S.-Mexico border? Can…
A new targeted alpha therapy is showing promise for patients whose thyroid cancer no longer responds to radioactive iodine, the standard beta-emitting treatment. In a first-in-human study, investigators found that a single dose of the…
UCLA scientists have characterized the structure and function of a key survival protein in breast cancer cells that helps explain how these tumors resist environmental stress and thrive in acidic, low-oxygen environments that would…
A new AI model could help radiologists identify brain abnormalities in MRI scans for all conditions including stroke, multiple sclerosis and brain tumors.
Microplastics could be fueling neurodegenerative diseases like Alzheimer's and Parkinson's, with a new study highlighting five ways microplastics can trigger inflammation and damage in the brain.
Huntsman Cancer Institute at the University of Utah (the U) participated in a clinical trial that found that a new combination treatment plan helped people with recurring grade 3 astrocytoma, an aggressive form of brain cancer, live longer.
In a study funded by the National Heart, Lung, and Blood Institute, new research from Johns Hopkins Medicine adds to existing evidence that smoking fewer cigarettes does not eliminate cardiovascular disease risk, and quitting entirely is…
First and foremost, we breathe in order to absorb oxygen - but this vital rhythm could also have other functions. Over the past few years, a range of studies have shown that respiration influences neural processes, including the processing…
Real progress in oral health doesn't come from expensive gadgets, but from better daily habits. That is the conclusion of dentist- periodontist Tim Thomassen in his dissertation Oral Disease Prevention, which he will defend on 12 December…
In a milestone moment for chronic pain management, Tonix Pharmaceuticals announced on August 15, 2025, that its novel sublingual therapy Tonmya has received approval from the U.S. Food and Drug Administration (FDA) - marking the first new…
Overweight as a child is not necessarily a risk factor for heart attack later in life. If weight is normalized before adulthood, the heart seems unaffected by the higher childhood BMI, according to a study conducted at the University of…
A new USC study shows teens with higher blood levels of per- and polyfluoroalkyl substances (PFAS) measured before bariatric surgery had smaller improvements in blood sugar over five years, including fasting glucose and hemoglobin A1c …