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03

How the Crimean-Congo hemorrhagic fever virus enters our cells

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Researchers have identified how the tick-borne Crimean-Congo haemorrhagic fever virus enters our cells. The results are an important step in the development of drugs against the deadly disease.

Thursday, Mar 28

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Positive associations between premenstrual disorders and perinatal depression

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Women affected by premenstrual disorders have a higher risk of perinatal depression compared with those who do not, according to new research. The relationship works both ways: those with perinatal depression are also more likely to…

21

Alcohol raises heart disease risk, particularly among women

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Young to middle-aged women who reported drinking eight or more alcoholic beverages per week--more than one per day, on average--were significantly more likely to develop coronary heart disease compared with those who drank less, finds a…

How built environment correlates with risk of cardiovascular disease

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Researchers have studied hundreds of elements of the built environment, including buildings, green spaces, pavements and roads, and how these elements relate to each other and influence coronary artery disease in people living in these…

Miscarriages linked to health risks in later pregnancies

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Researchers analyzed 52 studies involving more than 4 million pregnancies across 22 countries to investigate the health impacts of miscarriage, abortion and recurrent pregnancy loss (more than two miscarriages in succession) on subsequent…

20

'Exhausted' immune cells in healthy women could be target for breast cancer prevention

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People carrying BRCA1 and BRCA2 gene mutations are at high risk of developing breast and ovarian cancer. Researchers have found that changes occur in the immune cells of breast tissue in carriers of BRCA1 and BRCA2 mutations long before…

New method developed to isolate HIV particles

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Researchers have developed a new method to isolate HIV from samples more easily, potentially making it easier to detect infection with the virus. They focus on peptide nanofibrils (PNFs) on magnetic microparticles, a promising tool and…

19

Eggs may not be bad for your heart after all

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Whether you like your eggs sunny-side up, hard boiled or scrambled, many hesitate to eat them amid concerns that eggs may raise cholesterol levels and be bad for heart health. However, results from a prospective, controlled trial show that…

Parental avoidance of toxic exposures could help prevent autism, ADHD in children, new study shows

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Researchers have found that parents with chemical intolerance are more likely to report children with autism and ADHD.

17

Reverse effects of trauma? Older brain cells linger unexpectedly before their death

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Researchers report that mature oligodendrocytes -- the central nervous system cells critical for brain function -- cling to life following a fatal trauma for much, much longer than scientists knew. The findings suggest a new pathway for…

Clear shift in arterial diseases in diabetes

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There has been a redistribution in the risk of arterial disease in type 1 and 2 diabetes. The risks of heart attack and stroke have decreased significantly, while complications in more peripheral vessels have increased in relative…

13

Researchers introduce enhanced brain signal analysis technique

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Researchers have introduced a new, refined method for analyzing brain signals, enhancing our understanding of brain functionality. This research has the potential to improve treatments for neurological conditions such as Parkinson's…

New tool provides researchers with improved understanding of stem cell aging in the brain

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Researchers can use the light naturally thrown off by biological specimens to better study the different states of stem cells in the nervous system, thanks to a tool brightening their chances for studying the way stem cells age.

10

A combination of approved drugs enhances the delivery of anti-bacterial medications to treat tuberculosis

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Researchers have found that approved drugs that were originally shown to normalize blood vessels surrounding tumors (to improve drug delivery to cancer cells) can enhance the delivery of anti-microbial medications to kill tuberculosis…

Combining epigenetic cancer medications may have benefit for colorectal cancers and other tumor types

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A pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers and other solid tumors, reports a new study. The preclinical research determined how low doses of a DNMT…

Wednesday, Mar 27

22

Researchers turn back the clock on cancer cells to offer new treatment paradigm

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Scientists reversed an aggressive cancer, reverting malignant cells towards a more normal state. Rhabdoid tumors are an aggressive cancer which is missing a key tumor suppressor protein. Scientists discovered that removing a second protein…

Getting too little sleep linked to high blood pressure

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Sleeping fewer than seven hours is associated with a higher risk of developing high blood pressure over time, according to a new study.

Social, environmental factors may raise risk of developing heart disease and stroke

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Neighborhoods with more adversity have up to twice the increased risk of heart disease and stroke, according to a new study.

21

Earlier puberty onset may be one of the ways that childhood risk factors affect adult cardiometabolic health

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Experiencing puberty earlier, compared to same-age peers, may be one of the mechanisms through which childhood risk factors influence adult cardiometabolic health issues, according to a new study.

New technique for predicting protein dynamics may prove big breakthrough for drug discovery

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Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers has developed a way of using machine learning to rapidly predict multiple…

Risk factors for faster aging in the brain revealed in new study

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Researchers have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia.

Popular obesity drugs may lead to medical procedure complications

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New research suggests people who are scheduled for certain medical procedures should stop taking popular weight loss drugs in the days or weeks prior to avoid complications.

20

Safer, more efficient drug discovery

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Researchers have discovered a safer and more efficient technique for testing new drugs while they are in development.

Old immune systems revitalized in mouse study, improving vaccine response

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Those with aging immune systems struggle to fight off novel viruses and respond weakly to vaccination. Researchers were able to revitalize the immune system in mice.

19

Sweet success: Sugarcane's complex genetic code cracked

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Scientists created a highly accurate reference genome for one of the most important modern crops and found a rare example of how genes confer disease resistance in plants. Exploring sugarcane's genetic code could help researchers develop…

Researchers discover a mechanism that could improve platinum-based cancer therapy

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Researchers say they have discovered that the protein puromycin-sensitive aminopeptidase (NPEPPS) plays a role in regulating response to platinum chemotherapy in patients with bladder cancer.

Couples with similar drinking habits may live longer

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The couple that drinks together might live longer together, too, says a University of Michigan researcher.

Memory self-test via smartphone can identify early signs of Alzheimer's disease

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Dedicated memory tests on smartphones enable the detection of 'mild cognitive impairment', a condition that may indicate Alzheimer's disease, with high accuracy.

18

ADHD stimulants may increase risk of heart damage in young adults, study finds

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Young adults who were prescribed stimulant medications for attention-deficit/hyperactivity disorder (ADHD) were significantly more likely to develop cardiomyopathy (weakened heart muscle) compared with those who were not prescribed…

Want to feel young? Protect your sleep

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Do you ever find yourself longing for the energy and vitality of your younger years? Feeling young is not just a matter of perception it is actually related to objective health outcomes. Previous studies have shown that feeling younger…