For patients with non-small cell lung cancer with the epidermal growth factor receptor (EGFR) variant, ivonescimab plus chemotherapy improves progression-free survival, according to a study published online May 31 in the Journal of the…
Researchers at Osaka University have found that patients with steatotic liver disease who have high levels of growth differentiation factor 15 (GDF15) in their blood are more likely to develop liver cancer. By combining blood GDF15 levels…
A new PET radiotracer enables same-day imaging of the important gastrointestinal cancer biomarker known as Claudin18.2 (CLDN18.2). Uptake of the radiotracer, 68Ga-NC-BCH, was found to correlate significantly with CLDN18.2 expression, a…
AbbVie announced Phase 2 PICCOLO trial results for Elahere in heavily pre-treated ovarian cancer patients. The trial achieved a 51.9% objective response rate.
In an advance that could transform bladder cancer treatment, a novel combination of cretostimogene grenadenorepvec and pembrolizumab has shown remarkable efficacy in patients with Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle…
According to preliminary data from a multi-institution Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, intensity modulated proton therapy (IMPT) achieved similar clinical outcomes and offered…
Rita Fior, leader of the Cancer Development and Innate Immune Evasion Group at the Champalimaud Foundation (CF), has been studying for several years the power of zebrafish "avatars," or zAvatars, of cancer patients to help guide…
In a study including four glioblastoma patients scientists demonstrated the use of ultrasound technology and microbubbles to penetrate the blood-brain barrier and deliver liposomal doxorubicin and anti-PD-1 immunotherapy into the brain.…
Pancreatic cancer, recognized as one of the deadliest cancers, poses a persistent challenge for medical professionals globally due to its aggressive behavior and resistance to conventional therapies. The dense fibrotic tissue surrounding…
A short course of immunotherapy was found to be highly effective in a subset of patients with colon cancer. The treatment, which consisted of two cycles of immunotherapy prior to surgery, was effective in almost all patients. In two-thirds…
Phenotypic plasticity is a cancer hallmark, and lung adeno-to-squamous transition (AST) triggered by LKB1 inactivation is significantly associated with drug resistance. Clinical data show that squamous transition occurs in certain lung…
(MedPage Today) -- CHICAGO -- Use of metformin didn't prevent progression of low-risk localized prostate cancer in patients on active surveillance, according to data from the randomized MAST study.
(MedPage Today) -- CHICAGO -- Germline variations did not predict the risk of taxane-induced peripheral neuropathy (TIPN) in a phase II trial involving Black women with early-stage breast cancer, but the researchers found that docetaxel…
In a recent study led by Suresh Ramalingam, MD, executive director of Winship Cancer Institute of Emory University, a new drug has shown remarkable promise in treating patients with a specific type of advanced lung cancer.
New Mexico's Memorial Medical Center says it doesn't turn away patients. Thirteen cancer patients said they met with denials of care or demands for money up-front.