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Monday, Oct 20

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Cancer Study Links COVID Shots to Longer Survival

www.medpagetoday.com

(MedPage Today) -- BERLIN -- Non-small cell lung cancer (NSCLC) patients starting immunotherapy were nearly twice as likely to be alive 3 years later if they got a COVID-19 vaccine around the time of treatment, a researcher reported here.

Chemotherapy-Free Combo Improves Survival in Metastatic Colorectal Cancer

www.medpagetoday.com

(MedPage Today) -- BERLIN -- The investigational tyrosine kinase inhibitor (TKI) zanzalintinib plus atezolizumab (Tecentriq) significantly improved overall survival (OS) among previously treated patients with metastatic colorectal cancer,…

23

Who Knew? Autoimmunity Might Actually Benefit Some Cancer Patients

www.medpagetoday.com

(MedPage Today) -- Chimeric antigen receptor (CAR) T-cell therapy for blood cancers appeared less toxic, and patients' hospital stays were days shorter, when they also had autoimmune disease before starting the treatment, a large…

21

Colon cancer DNA may guide tailored post-surgery care

medicalxpress.com

Circulating tumor DNA (ctDNA)—genetic material shed from tumors into the bloodstream—may help risk-stratify patients with Stage 3 colon cancer by tailoring chemotherapy options after surgery based on risk of cancer recurrence, according to…

20

Combination of immunotherapy and targeted therapy boosts colorectal cancer survival, clinical trial finds

medicalxpress.com

A new study led by UCLA investigators found that combining zanzalintinib, a targeted therapy drug, and atezolizumab, an immune checkpoint inhibitor, helped patients with metastatic colorectal cancer, the second most common cause of cancer…

19

Blood test guides post-surgical immunotherapy for muscle-invasive bladder cancer

medicalxpress.com

Patients with muscle-invasive bladder cancer who test positive for circulating tumor (ct)DNA after surgery to remove the cancer benefit from immunotherapy with atezolizumab compared to placebo whereas ctDNA-negative patients may…

Digital health outreach can improve lung cancer screening

medicalxpress.com

A new multi-site study, published in JAMA, and co-led by researchers at the UNC Lineberger Comprehensive Cancer Center and Wake Forest University School of Medicine, has demonstrated that a direct-to-patient digital health program can…

De-Escalating Bone-Modifying Therapy Safe, Effective in Metastatic Breast Cancer

www.medpagetoday.com

(MedPage Today) -- BERLIN -- Administering bone-modifying agents (BMAs) every 24 weeks after long-term use was a safe and effective strategy for patients with bone metastases from breast cancer, and also appeared to be safe in prostate…

Study finds protein target that predicts drug resistance in colon cancer

medicalxpress.com

An international team of researchers has uncovered a promising new avenue for treating colorectal cancer, the world's third leading cause of cancer-related deaths. By analyzing patient-specific genetic data, scientists identified a protein…

18

New generation of antibody-drug conjugates shows promise in early-stage HER2-positive breast cancer

medicalxpress.com

In a landmark moment at the ESMO Congress 2025, pivotal studies have unveiled compelling evidence that a new class of anti-cancer agents—antibody-drug conjugates (ADCs)—can dramatically improve outcomes for patients with early-stage HER2…

Simple blood test can pick up cancer cases in ‘false positive’ patients – study

www.expressandstar.com

The Galleri blood test by Grail can be given annually and looks for the DNA ‘fingerprint’ of more than 50 deadly cancers.

Simple blood test can pick up cancer cases in ‘false positive’ patients – study

www.shropshirestar.com

The Galleri blood test by Grail can be given annually and looks for the DNA ‘fingerprint’ of more than 50 deadly cancers.

Simple blood test can pick up cancer cases in ‘false positive’ patients – study

www.standard.co.uk

The Galleri blood test by Grail can be given annually and looks for the DNA ‘fingerprint’ of more than 50 deadly cancers.

Scientists find immune drug that could halt skin cancer’s deadly spread

www.sciencedaily.com

Researchers found that pembrolizumab, an immune-activating cancer drug, lowered the risk of distant metastases in patients with Merkel cell carcinoma after surgery. Though recurrence rates overall weren’t significantly changed, the results…

Protective immune cells in breastfeeding women identified as guard against breast cancer, new research finds

www.theguardian.com

Patients who had more cells had better outcomes, particularly for aggressive types such as triple-negative breast cancer

17

Trop2 Drug Extends Survival in EGFR-Mutated Lung Cancer

www.medpagetoday.com

(MedPage Today) -- BERLIN -- An antibody-drug conjugate targeting Trop2 significantly improved survival outcomes compared with platinum-based chemotherapy in pretreated patients with EGFR-mutated non-small cell lung cancer (NSCLC), a…

Oral drug demonstrates promising anti-tumor activity in patients with advanced lung cancer

medicalxpress.com

The oral targeted therapy sevabertinib led to tumor reduction and manageable side effects in patients with HER2-mutant non-small cell lung cancer (NSCLC), according to data from a trial led by researchers at The University of Texas MD…

16

This common vitamin could cut your skin cancer risk in half

www.sciencedaily.com

A massive Veterans Affairs study has confirmed that nicotinamide may offer real protection against skin cancer. Patients who took the vitamin B3 derivative saw notable reductions in new cancer cases—especially squamous cell carcinomas. The…

14

Business News | Clinicians at Fortis' S.L. Raheja Hospital Successfully Perform 1st Bone Marrow Transplant, Marking a Major Milestone in Advanced Cancer Care

www.latestly.com

Get latest articles and stories on Business at LatestLY. Mumbai (Maharashtra) [India], October 20: S.L. Raheja Hospital, Mahim - A Fortis Associate, has achieved a milestone in its clinical journey with the successful completion of its…

Are cancer surgeries removing the body’s secret weapon against cancer?

www.sciencedaily.com

Scientists have found that preserving lymph nodes during cancer surgery could dramatically improve how patients respond to immunotherapy. The research shows that lymph nodes are essential for training and sustaining cancer-fighting T cells…